Article

A versatile data repository for GWAS summary statistics-based downstream genomic analysis of human complex traits

2025-10-02

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of loci associated with complex traits and diseases, yet the biological interpretation of these findings remains limited. We developed gact, an R package that integrates GWAS summary statistics with diverse genomic resources to facilitate the discovery of causal genes, pathways, and disease mechanisms. The package enables construction of a local data...

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Literature Corpus work: faf835da-ed7d-58fa-b96e-6a3d34f12efd
DOI: 10.1101/2025.10.01.25337099

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