Article

Partitioning heritability by functional category using GWAS summary statistics

2015-01-23

Abstract excerpt

Recent work has demonstrated that some functional categories of the genome contribute disproportionately to the heritability of complex diseases. Here, we analyze a broad set of functional elements, including cell-type-specific elements, to estimate their polygenic contributions to heritability in genome-wide association studies (GWAS) of 17 complex diseases and traits spanning a total of 1.3 million phenotype mea...

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Literature Corpus work: cac80d75-9a17-54f3-aefb-2bdc82218b0c
DOI: 10.1101/014241

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