Article

Genetic and microbial determinants of azoxymethane-induced colorectal tumor susceptibility in Collaborative Cross mice and their implication in human cancer

2023-11-01

Abstract excerpt

<title>Abstract</title> <p>Background The insights into interactions between host genetics and gut microbiome (GM) in colorectal tumor susceptibility (CTS) remains lacking. We used Collaborative Cross mouse population model to identify genetic and microbial determinants of Azoxymethane-induced CTS. Results We identified 4417 CTS-associated SNPs containing 936 known human genes, 334 of which were found to be tra...

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Literature Corpus work: a912a133-ca36-57f7-81bd-cbb414a79f60
DOI: 10.21203/rs.3.rs-3492024/v1

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