Article

Host Genetics Background Affects the Intestinal Cancer Development Associated with High-fat Diet-induced Obesity and Type 2 Diabetes

2024-09-14

Abstract excerpt

<h4>Background: </h4> Obesity and Type 2 diabetes (T2D) promote inflammation, increasing the risk of colorectal cancer (CRC). High-fat diet (HFD)-induced obesity plays a key role in these diseases through biological mechanisms. This study examined the effect of genetic background on the multimorbidity of intestinal cancer, T2D, and inflammation due to HFD-induced obesity. <h4>Methods:</h4> A cohort of 357 Collabor...

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Literature Corpus work: 2d2f5a0c-2aa6-58dc-8076-46e4be8632e9
DOI: 10.20944/preprints202409.1094.v1

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