Article

Domain-specific proteome remodeling defines mouse myelin aging

2026-07-09

Abstract excerpt

Myelin, once regarded as a static insulating structure, is now recognized as a dynamic component of the nervous system, capable of remodeling in response to experience. Its breakdown is linked to cognitive decline and neurodegenerative diseases, often preceding neuronal dysfunction. While the myelin proteome has been studied, the age- and sex-related changes it undergoes remain poorly understood. In this study, we...

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Literature Corpus work: d142e8f1-d734-5180-8140-a4528de748d3
DOI: 10.64898/2026.07.05.736479

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