Article
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.
eLife - 4 Mar 2020
Siems Sophie B, Jahn Olaf, Eichel Maria A, Kannaiyan Nirmal, Wu Lai Man N, Sherman Diane L, Kusch Kathrin, Hesse Dörte, Jung Ramona B, Fledrich Robert, Sereda Michael W, Rossner Moritz J, Brophy Peter J, Werner Hauke B
Abstract excerpt
Proteome and transcriptome analyses aim at comprehending the molecular profiles of the brain, its cell-types and subcellular compartments including myelin. Despite the relevance of the peripheral nervous system for normal sensory and motor capabilities, analogous approaches to peripheral nerves and peripheral myelin have fallen behind evolving technical standards. Here we assess the peripheral myelin proteome by...
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