Article

Integrative Computational Analysis of <em>TP53 </em>Exon 5–6 Mutations in Oral Cavity, Prostate, and Breast Cancers in a Senegalese Population

2026-01-23

Abstract excerpt

<h4>Background: </h4> /Objectives: The tumor suppressor gene TP53 is one of the most frequently mutated genes in human cancers, with alterations predominantly affecting its DNA-binding domain (DBD). However, the mutational landscape and functional consequences of TP53 variants remain poorly characterized in African populations. This study aimed to characterize mutations in exons 5-6 of TP53 in oral cavity cancer (...

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Literature Corpus work: fa8c6d32-e7e3-5187-a35e-b41a54b18d6c
DOI: 10.20944/preprints202601.1829.v1

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