Article

Phenotypical mapping of TP53 unique missense mutations spectrum in human cancers

2023-02-06

Abstract excerpt

The p53 tumor suppressor is one of the most mutated genes responsible for tumorigenesis in most human cancers. Out of 29,891 genomic mutations reported in the TP53 Database ( https://tp53.isb-cgc.org/ ), 1297 are identified as unique missense somatic mutants excluding frameshift, intronic, deletion, nonsense, silent, splice and other unknown mutations. we have comprehensively analyzed all these 1297 unique missen...

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Literature Corpus work: b43a997a-611f-5977-b593-844a3679ad28
DOI: 10.1101/2023.02.06.527255

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