Article

Molecular and in-silico analysis of single nucleotide polymorphism targeting human TP53 gene exon 5-8 in Sudanese esophageal cancer patients

2018-11-02

Abstract excerpt

<h4>Background: </h4> The protein product of the normal TP53 gene performs an essential function in cell cycle control and tumor suppression, and the mutation of a TP53 gene is an essential step in the development of many cancers. Despite the reported association of TP53 gene mutations with many human cancers, the comprehensive computational analysis of single nucleotide polymorphisms (SNPs), and their function...

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Literature Corpus work: e22e67ad-6e67-5e52-a6ec-22a6680de544
DOI: 10.12688/f1000research.15534.1

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