Article

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

2023-12-14

Abstract excerpt

The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. Here, we generated macrophages from cryopreserved blood mononuclear cells of Tanzanian tuberculosis patients, from which the infecting MTBC strains had previously bee...

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Literature Corpus work: fa725907-c910-52bb-84b9-f656520b7f9e
DOI: 10.1101/2023.12.13.571507

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