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The within-host evolution of antimicrobial resistance in Mycobacterium tuberculosis

12 Dec 2020

Abstract excerpt

Tuberculosis (TB) has been responsible for the greatest number of human deaths due to an infectious disease in general, and due to antimicrobial resistance (AMR) in particular. The etiological agents of human TB are a closely-related group of human-adapted bacteria that belong to the Mycobacterium tuberculosis complex (MTBC). Understanding how MTBC populations evolve within-host may allow for improved TB...

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PMID: 33320947
DOI: 10.1093/femsre/fuaa071

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