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Article

Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages.

PLoS pathogens - 1 Mar 2011

Portevin Damien, Gagneux Sébastien, Comas Iñaki, Young Douglas

Abstract excerpt

The aim of the present study was to determine whether there is a correlation between phylogenetic relationship and inflammatory response amongst a panel of clinical isolates representative of the global diversity of the human Mycobacterium tuberculosis Complex (MTBC). Measurement of cytokines from infected human peripheral blood monocyte-derived macrophages revealed a wide variation in the response to different...

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Identifiers

PMID: 21408618
DOI: 10.1371/journal.ppat.1001307
PMCID: PMC3048359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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