Article
Diversity of Mycobacterium tuberculosis across Evolutionary Scales.
PLoS pathogens - 1 Jan 2015
O'Neill Mary B, Mortimer Tatum D, Pepperell Caitlin S
Abstract excerpt
Tuberculosis (TB) is a global public health emergency. Increasingly drug resistant strains of Mycobacterium tuberculosis (M.tb) continue to emerge and spread, highlighting adaptability of this pathogen. Most studies of M.tb evolution have relied on 'between-host' samples, in which each person with TB is represented by a single M.tb isolate. However, individuals with TB commonly harbor populations of M.tb...
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