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Article

Shaping the niche in macrophages: Genetic diversity of the M. tuberculosis complex and its consequences for the infected host.

International journal of medical microbiology : IJMM - 1 Jan 2018

Reiling Norbert, Homolka Susanne, Kohl Thomas A, Steinhäuser Christine, Kolbe Katharina, Schütze Stefan, Brandenburg Julius

Abstract excerpt

Pathogenic mycobacteria of the Mycobacterium tuberculosis complex (MTBC) have co-evolved with their individual hosts and are able to transform the hostile environment of the macrophage into a permissive cellular habitat. The impact of MTBC genetic variability has long been considered largely unimportant in TB pathogenesis. Members of the MTBC can now be distinguished into three major phylogenetic groups...

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Identifiers

PMID: 28969988
DOI: 10.1016/j.ijmm.2017.09.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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