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Soluble immune mediators orchestrate protective <i>in vitro</i> granulomatous responses across <i>Mycobacterium tuberculosis</i> complex lineages

2024-05-23

Abstract excerpt

<h4>ABSTRACT</h4> The members of the Mycobacterium tuberculosis complex (MTBC) causing human tuberculosis comprise ten phylogenetic lineages that differ in their geographical distribution. The human consequences of this phylogenetic diversity remain poorly understood. Here, we assessed the phenotypic properties at the host-pathogen interface of 14 clinical strains representing five major MTBC lineages. Using a h...

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Literature Corpus work
76ab420b-c9c2-5748-86d5-a96e67886e39
DOI
10.1101/2024.05.21.595219
Open publication

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Soluble immune mediators orchestrate protective <i>in vitro</i> granulomatous responses across <i>Mycobacterium tuberculosis</i> complex lineagesDOI 10.1101/2024.05.21.595219
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