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FADS2 Function at the Major Cancer Hotspot 11q13 Locus Alters Fatty Acid Metabolism in Cancer

2022-10-14

Abstract excerpt

The human chromosome 11q13 (HSA 11q13) genomic locus is a major cancer hotspot and has been established as the most frequently altered by amplification in a variety of human cancers. The fatty acid desaturase genes (FADS1, FADS2 and FADS3) localize to the 11q12- 13.1 region. FADS2 activity is promiscuous, catalyzing biosynthesis of polyunsaturated and monounsaturated fatty acids, including unsaturated branched cha...

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Literature Corpus work
fa54de20-2d90-5add-ad8d-48ea626003d8
DOI
10.20944/preprints202210.0206.v1
Open publication

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FADS2 Function at the Major Cancer Hotspot 11q13 Locus Alters Fatty Acid Metabolism in CancerDOI 10.20944/preprints202210.0206.v1
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