Article

An Integrative Pan-Cancer Analysis of FASN in Human Tumors

2022-06-01

Abstract excerpt

<h4>Background: </h4> The reprogramming of lipid metabolism in tumor cells has led to a new focus on the study of lipid metabolism, which provides raw materials and energy for tumor cell growth and also serves as an intracellular second messenger involved in cell growth and proliferation. There is increasing evidence that fatty acid synthase( FASN), a key enzyme in lipid metabolism, is overexpressed in many cancer...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 35778cc3-b8d9-5944-882f-402824498f8d
DOI: 10.21203/rs.3.rs-1698683/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An Integrative Pan-Cancer Analysis of FASN in Human TumorsDOI 10.21203/rs.3.rs-1698683/v1Read

Prognostic Value of Fatty Acid Synthase FASN in Renal Clear Cell Carcinoma and Bioinformatics Analysis of Immune CorrelationSemantic proximity Read

SREBF1 is a Potential Prognostic and Immunological Biomarker in Pan-CancerSemantic proximity Read

Molecular Pathways: Fatty Acid SynthaseSemantic proximity Read

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.Semantic proximity Read

The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomesSemantic proximity Read

Development of a novel lipid metabolism-based signature to predict survival and immune response in triple negative breast cancerSemantic proximity Read

A comprehensive analysis of the potential biological functions and prognostic values of SREBF1 for multiple cancer types including colorectal cancerSemantic proximity Read

Fatty acid synthase (FASN), a novel signature for visceral adipose tissues, regulates proliferation, migration and predicts prognosis of clear cell renal cell carcinomaSemantic proximity Read

Systematic pan-cancer analysis identifies 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) as a biomarker of tumor invasion and metastasis, immunity, and prognosisSemantic proximity Read

FASTKD1 is a diagnostic and prognostic biomarker for STAD associated with m6A modification and immune infiltrationSemantic proximity Read

Pan-cancer Analyses Reveal Regulation and Clinical Outcome Association of the PCLAF in Human TumorsSemantic proximity Read

Identification of fatty acids synthesis and metabolism-related gene signature and prediction of prognostic model in hepatocellular carcinomaSemantic proximity Read