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Article

Systematic analysis of fatty acid desaturases in breast invasive carcinoma: The prognosis, gene mutation, and tumor immune microenvironment.

Medicine - 21 Jun 2024

Wang Jie, Zhang Qian, Zhou Duanrui, Wang Yixuan, Che Huilian, Ge Yunjun, Zhong Zhangfeng, Wu Guosheng

Abstract excerpt

Breast invasive carcinoma (BRCA) is one of the most common cancers in women, with its malignant progression significantly influenced by intracellular fatty acid (FA) desaturation. Stearoyl-coenzyme A desaturase (SCD) and fatty acid desaturase 2 (FADS2) are two key rate-limiting enzymes that catalyze the FA desaturation process and cooperate to accelerate lipid metabolic activities. In this study, we investigated...

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Identifiers

PMID: 38905386
DOI: 10.1097/MD.0000000000038597
PMCID: PMC11191958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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