Article

Extracellular DNASE1L3 dysfunction fuels obesity-driven inflammation and metabolic syndrome

2026-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Obesity, a global health crisis affecting 16% of the world population, is characterized by chronic inflammation that contributes to health complications such as type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD). Emerging evidence suggests that self-DNA released from dying cells aberrantly activates inflammatory responses during obesity. However, the role of ext...

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Literature Corpus work: fa27d15f-a160-5232-9df7-949fba968e7d
DOI: 10.64898/2026.03.23.713589

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