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Mitochondrial DNA DAMPs Induce Inflammation and Insulin Resistance

2018-06-22

Abstract excerpt

Increasing evidence showed that mitochondrial DNA (mtDNA), as a part of mitochondrial damage-associated molecular patterns (DAMPs), induces an immune response and inflammation in immune, as well as in cells of nonnimmune origin. As insulin resistance and type 2 diabetes are characterized by a persistent chronic inflammation, the aim if this study was to evaluate if mtDNA DAMPs induce an inflammatory responses in s...

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Identifiers and source

Literature Corpus work
293e0d35-455f-5562-a7f7-09fe55f74b78
DOI
10.2337/db18-1783-p
Open publication

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Mitochondrial DNA DAMPs Induce Inflammation and Insulin ResistanceDOI 10.2337/db18-1783-p
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