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ATGL-catalyzed lipid catabolism promotes DNA double-strand break repair

2026-04-04

Abstract excerpt

<h4>ABSTRACT</h4> An imbalance of DNA damage over DNA repair contributes to the genomic instability that drives aging and numerous age-related diseases. While numerous DNA repair mechanisms have been elucidated over decades of study, little is known about the contribution of metabolism to genomic stability. We report that adipose triglyceride lipase (ATGL), a lipolytic enzyme, promotes DNA repair. We show that li...

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Literature Corpus work
56caf888-dee3-5b77-8248-e9a538c5aa92
DOI
10.64898/2026.04.03.716381
Open publication

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