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Article

Cidea improves the metabolic profile through expansion of adipose tissue.

Nature communications - 29 Jun 2015

Abreu-Vieira Gustavo, Fischer Alexander W, Mattsson Charlotte, de Jong Jasper M A, Shabalina Irina G, Rydén Mikael, Laurencikiene Jurga, Arner Peter, Cannon Barbara, Nedergaard Jan, Petrovic Natasa

Abstract excerpt

In humans, Cidea (cell death-inducing DNA fragmentation factor alpha-like effector A) is highly but variably expressed in white fat, and expression correlates with metabolic health. Here we generate transgenic mice expressing human Cidea in adipose tissues (aP2-hCidea mice) and show that Cidea is mechanistically associated with a robust increase in adipose tissue expandability. Under humanized conditions...

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Source

Identifiers

PMID: 26118629
DOI: 10.1038/ncomms8433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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