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Neuroimaging PheWAS and molecular phenotyping implicate <i>PSMC3</i> in Alzheimer’s Disease

2025-09-19

Abstract excerpt

<h4>INTRODUCTION</h4> Neuroimaging genetics have advanced Alzheimer’s disease (AD) research, yet frameworks mechanistically connecting genes to neurological outcomes via functional genomics are needed to elucidate genetic associations. To address this challenge, we assessed relationships between AD-associated variants and disease via their impact on gene expression and neuroimaging phenotypes. <h4>METHODS</h4> W...

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Literature Corpus work: fa246642-248f-57a4-a029-e9760f9f2eb5
DOI: 10.1101/2025.09.18.25336095

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