Article
Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort.
NeuroImage - 15 Nov 2010
Shen Li, Kim Sungeun, Risacher Shannon L, Nho Kwangsik, Swaminathan Shanker, West John D, Foroud Tatiana, Pankratz Nathan, Moore Jason H, Sloan Chantel D, Huentelman Matthew J, Craig David W, Dechairo Bryan M, Potkin Steven G, Jack Clifford R, Weiner Michael W, Saykin Andrew J
Abstract excerpt
A genome-wide, whole brain approach to investigate genetic effects on neuroimaging phenotypes for identifying quantitative trait loci is described. The Alzheimer's Disease Neuroimaging Initiative 1.5 T MRI and genetic dataset was investigated using voxel-based morphometry (VBM) and FreeSurfer par...
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