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Genetic associations of in vivo pathology influence Alzheimer’s disease susceptibility

19 Nov 2020

Abstract excerpt

INTRODUCTION: Although the heritability of sporadic Alzheimer's disease (AD) is estimated to be 60-80%, addressing the genetic contribution to AD risk still remains elusive. More specifically, it remains unclear whether genetic variants are able to affect neurodegenerative brain features that can be addressed by in vivo imaging techniques. METHODS: F-fluorodeoxyglucose PET, and MRI that are available from the...

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PMID: 33213512
DOI: 10.1186/s13195-020-00722-2

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