Article

Clonal hematopoiesis of indeterminate potential is associated with worse kidney function and anemia in a cohort of patients with advanced chronic kidney disease

2021-07-02

Abstract excerpt

<h4>Background</h4> Clonal hematopoiesis of indeterminate potential (CHIP) is an inflammatory premalignant disorder resulting from acquired genetic mutations in hematopoietic stem cells. CHIP is common in aging populations and associated with cardiovascular morbidity and overall mortality, but its role in chronic kidney disease (CKD) has not been investigated. <h4>Methods</h4> We performed targeted sequencing to d...

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Literature Corpus work: f9f7e6ae-61df-58af-9435-1735e6286053
DOI: 10.1101/2021.06.30.21259343

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