Article

Clonal Hematopoiesis of Indeterminate Potential Refines Cardiovascular Risk Stratification in Cardiovascular-Kidney-Metabolic Syndrome Stages 0–3

2026-06-08

Abstract excerpt

<h4>Background</h4> Chronic low-grade inflammation drives cardiovascular-kidney-metabolic (CKM) syndrome. Clonal hematopoiesis of indeterminate potential (CHIP), an age-related driver of systemic inflammation, is linked to several cardiometabolic disorders. However, whether CHIP modifies CKM progression and contributes to heterogeneity in cardiovascular disease (CVD) risk within the CKM framework remains uninvest...

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Literature Corpus work: 4511d2a5-01c6-5915-828e-68978702071d
DOI: 10.64898/2026.06.04.26354963

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