Clonal haematopoiesis of indeterminate potential and impaired kidney function-A Danish general population study with 11 years follow-up.

doi:10.1111/ejh.13845

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Clonal haematopoiesis of indeterminate potential and impaired kidney function-A Danish general population study with 11 years follow-up.

European journal of haematology - 1 Nov 2022

Larsen Morten K, Skov Vibe, Kjaer Lasse, Møller-Palacino Natascha A, Pedersen Rasmus K, Andersen Morten, Ottesen Johnny T, Cordua Sabrina, Poulsen Henrik E, Dahl Morten, Knudsen Trine A, Eickhardt-Dalbøge Christina Schjellerup, Koschmieder Steffen, Pedersen Kasper M, Çolak Yunus, Bojesen Stig E, Nordestgaard Børge G, Stiehl Thomas, Hasselbalch Hans C, Ellervik Christina

Abstract excerpt

The myeloproliferative neoplasms are associated with chronic kidney disease but whether clonal haematopoiesis of indeterminate potential (CHIP) is associated with impaired kidney function is unknown. In the Danish General Suburban Population Study (N = 19 958) from 2010 to 2013, 645 individuals were positive for JAK2V617F (N = 613) or CALR (N = 32) mutations. Mutation-positive individuals without haematological...

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PMID: 36054308
DOI: 10.1111/ejh.13845
PMCID: PMC9804367

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