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Article

Clonal haematopoiesis, ageing and kidney disease.

Nature reviews. Nephrology - 1 Mar 2024

Vlasschaert Caitlyn, Lanktree Matthew B, Rauh Michael J, Kelly Tanika N, Natarajan Pradeep

Abstract excerpt

Clonal haematopoiesis of indeterminate potential (CHIP) is a preclinical condition wherein a sizeable proportion of an individual's circulating blood cells are derived from a single mutated haematopoietic stem cell. CHIP occurs frequently with ageing - more than 10% of individuals over 65 years of age are affected - and is associated with an increased risk of disease across several organ systems and premature...

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Identifiers

PMID: 37884787
DOI: 10.1038/s41581-023-00778-x
PMCID: PMC10922936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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