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Article

Emerging evidence on the role of clonal hematopoiesis of indeterminate potential in chronic kidney disease.

Translational research : the journal of laboratory and clinical medicine - 1 Jun 2023

Huang Zhijie, Vlasschaert Caitlyn, Robinson-Cohen Cassianne, Pan Yang, Sun Xiao, Lash James P, Kestenbaum Bryan, Kelly Tanika N

Abstract excerpt

Chronic kidney disease (CKD) was responsible for 1.2 million deaths globally in 2016. Despite the large and growing burden of CKD, treatment options are limited and generally only preserve kidney function. Characterizing molecular precursors to incident and progressive CKD could point to critically needed prevention and treatment strategies. Clonal hematopoiesis of indeterminate potential (CHIP) is typically...

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Identifiers

PMID: 36586535
DOI: 10.1016/j.trsl.2022.12.009
PMCID: PMC10101890

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