Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury.

doi:10.1038/s41591-024-02854-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury.

Nature medicine - 1 Mar 2024

Vlasschaert Caitlyn, Robinson-Cohen Cassianne, Chen Jianchun, Akwo Elvis, Parker Alyssa C, Silver Samuel A, Bhatraju Pavan K, Poisner Hannah, Cao Shirong, Jiang Ming, Wang Yinqiu, Niu Aolei, Siew Edward, Van Amburg Joseph C, Kramer Holly J, Kottgen Anna, Franceschini Nora, Psaty Bruce M, Tracy Russell P, Alonso Alvaro, Arking Dan E, Coresh Josef, Ballantyne Christie M, Boerwinkle Eric, Grams Morgan, Zhang Ming-Zhi, Kestenbaum Bryan, Lanktree Matthew B, Rauh Michael J, Harris Raymond C, Bick Alexander G

Abstract excerpt

Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential (CHIP) confers increased risk for several chronic diseases associated with aging. Here we sought to test whether CHIP increases the risk of AKI. In three population-based epidemiology cohorts, we found that CHIP was associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aging

Share to Clonal Hematopoiesis

Share to DNMT3A gene

Share to Hematopoiesis

Share to Mice

Share to Mutation

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 38454125
DOI: 10.1038/s41591-024-02854-6
PMCID: PMC10957477

Genes

DNMT3A
JAK2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury.PMID 38454125Read ↗

Clonal Hematopoiesis of Indeterminate Potential is Associated with Acute Kidney InjurySemantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential contributes to accelerated chronic kidney disease progressionSemantic proximity Read ↗

Epigenetic roles in clonal hematopoiesis and aging kidney-related chronic kidney diseaseSemantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential: a review of its cardiorenal implications and agingSemantic proximity Read ↗

Emerging evidence on the role of clonal hematopoiesis of indeterminate potential in chronic kidney disease.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential is associated with worse kidney function and anemia in a cohort of patients with advanced chronic kidney diseaseSemantic proximity Read ↗

Clonal haematopoiesis, ageing and kidney disease.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases.Semantic proximity Read ↗

Clonal Hematopoiesis of Indeterminate Potential and Kidney Failure in CKD: An East Asian Cohort Study.Semantic proximity Read ↗

Clonal hematopoiesis and associated diseases: A review of recent findings.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease.Semantic proximity Read ↗

CHIP In cardiovascular and immune ageing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.