Article

Wilms tumor mutational subclasses converge to drive<i>CCND2</i>overexpression

2023-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Wilms tumor, the most common kidney cancer in pediatrics, arises from embryonic renal progenitors. Although many patients are cured with multimodal therapy, outcomes remain poor for those with high-risk features. Recent sequencing efforts have provided few biological or clinically actionable insights. Here, we performed DNA and RNA sequencing on 94 Wilms tumors to understand how Wilms tumor mutat...

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Literature Corpus work: f9f69365-5cb7-5576-98c4-d04700c5788b
DOI: 10.1101/2023.01.30.23285117

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