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Hexokinase domain-containing protein-1 in metabolic diseases and beyond

12 Nov 2021

Abstract excerpt

Hexokinase (HK) domain-containing protein-1 (HKDC1) is a widely expressed novel HK.Recent studies aimed at understanding the functionality of HKDC1 have identified roles for HKDC1 that extend beyond glucose sensing and phosphorylation.Genome-wide association studies have identified genetic variants of HKDC1 that are associated with 2-h blood glucose levels during an oral glucose tolerance test performed in...

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PMID: 34782236
DOI: 10.1016/j.tem.2021.10.006

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