Article

Single Cell Analysis Dissects the Effects of Vitamin D on Genetic Senescent Signatures Across Murine Tissues

2024-12-20

Abstract excerpt

Vitamin D (VD) plays a crucial role in age-related diseases, and its influence on cellular senescence (CS) could help clarify its function in aging. Considering VD’s pleiotropic effects and the heterogeneity of CS, we utilized single-cell RNA sequencing (scRNA-seq) to explore these dynamics across multiple tissues. We analyzed three murine tissue datasets (bone, prostate, and skin) obtained from public repositorie...

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Literature Corpus work: f9c84e52-8966-5bc3-80e3-22df72ab1a36
DOI: 10.20944/preprints202412.1732.v1

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