Article

Natural selection influenced the genetic architecture of brain structure, behavioral and neuropsychiatric traits

2020-02-27

Abstract excerpt

Natural selection has shaped the phenotypic characteristics of human populations. Genome-wide association studies (GWAS) have elucidated contributions of thousands of common variants with small effects on an individual’s predisposition to complex traits (polygenicity), as well as wide-spread sharing of risk alleles across traits in the human phenome (pleiotropy). It remains unclear how the pervasive effects of nat...

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Literature Corpus work: f9c2836e-df1a-53bc-9c3b-ffebf9d7d44b
DOI: 10.1101/2020.02.26.966531

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