Article

Genetic architectures of brain-related traits are shaped by strong selective constraints

2026-03-25

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of significant loci for psychiatric disorders, yet the strength of these associations remains modest compared to other human complex traits with similar numbers of hits. Whether this pattern reflects statistical artifacts or real biological differences — and, if the latter, what underlies it — remains unclear. In addition to psychiatric disorders, we...

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Literature Corpus work: 2c8378e2-f3b5-5002-813b-02414948aab4
DOI: 10.64898/2026.03.22.713538

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