Article

Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity

2023-08-31

Abstract excerpt

Gut-associated lymphoid tissue (GALT) is organised lymphoid tissue that is chronically activated by the intestinal microbiota. It generates the IgA response that is critical for intestinal homeostasis. By iterative application of multiplexed technologies, we identify enrichment of double-negative 2 (DN2:CD27 - IgD - CD21 lo CD11c hi ) B cells in GALT, where they comprise the majority of intraepithelial and sub...

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Literature Corpus work: f996f89c-39e0-5bf2-9e4c-be2e76bebefc
DOI: 10.1101/2023.08.29.555265

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