Article

Immune signaling mediates stromal changes to support epithelial reprogramming in Celiac duodenum

2025-03-10

Abstract excerpt

Coeliac Disease (CeD) is a chronic autoimmune disorder affecting 0.5-1% of the general population with a wide geographical distribution. Despite recent efforts to deeply phenotype gluten-specific immune activation at the single cell level, recent clinical studies targeting gluten degradation and other immune tolerance mechanisms have been unsuccessful. To this end, a deeper understanding of immune and non-immune c...

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Literature Corpus work: a3ee0e00-af5d-50b6-be50-517057ff1225
DOI: 10.1101/2025.03.05.641653

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