Article

IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

2021-08-30

Abstract excerpt

<h4>Summary</h4> Mammals produce large quantities of mucosal and systemic antibodies that maintain the intestinal barrier, shape the intestinal microbiome and promote lifelong mutualism with commensal microbes. Here, we developed an integrated host-commensal approach combining microbial flow cytometry and 16s rRNA gene sequencing to define the core microbes that induce mucosal and systemic antibodies in pediatric...

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Literature Corpus work: 1ebe0ed0-dbeb-5b36-943c-0e49cd7e6363
DOI: 10.1101/2021.08.20.21261620

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