Article

Estimation of inbreeding and kinship coefficients via latent identity-by-descent states

2023-09-06

Abstract excerpt

Estimating the individual inbreeding coefficient and pairwise kinship is an important problem in human genetics (e.g., in disease mapping) and in animal and plant genetics (e.g., inbreeding design). Existing methods such as sample correlation-based genetic relationship matrix, KING, and UKin are either biased, or not able to estimate inbreeding coefficients, or produce a large proportion of negative estimates that...

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Literature Corpus work: f9768775-6669-59b0-922a-7d0b02cd69a0
DOI: 10.1101/2023.09.02.556031

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