Article
Inference of relationships in population data using identity-by-descent and identity-by-state.
PLoS genetics - 1 Sept 2011
Stevens Eric L, Heckenberg Greg, Roberson Elisha D O, Baugher Joseph D, Downey Thomas J, Pevsner Jonathan
Abstract excerpt
It is an assumption of large, population-based datasets that samples are annotated accurately whether they correspond to known relationships or unrelated individuals. These annotations are key for a broad range of genetics applications. While many methods are available to assess relatedness that...
Topics
- Algorithms
- Alleles
- Computer Simulation
- Data Interpretation, Statistical
- Genetic Linkage
- Genome, Human
- Genome-Wide Association Study
- Genotype
- Haplotypes
- Homozygote
- Humans
- Markov Chains
- Pedigree
- Polymorphism, Single Nucleotide
- Software