Article
Unexpected relationships and inbreeding in HapMap phase III populations.
PloS one - 1 Jan 2012
Stevens Eric L, Baugher Joseph D, Shirley Matthew D, Frelin Laurence P, Pevsner Jonathan
Abstract excerpt
Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap phase III data. We analyzed data from 1,397 individuals across 11 ethnic populations. Our results support previous...
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