Article

Cell competition reprograms adherent-suspension plasticity in disseminated tumor cells

2024-11-28

Abstract excerpt

Cell competition within the primary tumor drives tumor growth by promoting the uncontrolled proliferation of winner cells and eliminating loser cells by sensing cell fitness. However, the mechanism of how cell competition confers the loser cells with the metastatic potential of circulating tumor cells (CTCs) to transit between dissemination and colonization remains elusive. Here we found cell competition gives ris...

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Literature Corpus work: f97519fc-3e56-5c6a-89dd-7136b9fc91ab
DOI: 10.1101/2024.11.25.625320

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