Article
The bone microenvironment invigorates metastatic seeds for further dissemination
2020-11-16
Abstract excerpt
<h4>SUMMARY</h4> Metastasis has been considered as the terminal step of tumor progression. However, recent clinical studies suggest that many metastases are seeded from other metastases, rather than primary tumors. Thus, some metastases can further spread, but the corresponding pre-clinical models are lacking. By using several approaches including parabiosis and an evolving barcode system, we demonstrated that th...
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Identifiers and source
- Literature Corpus work
- 736bbed9-b297-576b-98b9-0681ce241352
- DOI
- 10.1101/2020.11.16.383828