Back to search

Article

In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in monkey brain

2022-10-24

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>: <sup>18</sup>F-SF51 was previously found to have high binding affinity and selectivity for 18kDa translocator protein (TSPO) in mouse brain. This study sought to further evaluate the suitability of <sup>18</sup>F-SF51 for absolute quantification of TSPO in monkey brain. <bold>Methods: </bold>Positron emission tomography (PET) imaging was performed in monkey brain (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f95a97e9-bf41-5786-a38c-ec78bfab63df
DOI
10.21203/rs.3.rs-2167175/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in monkey brainDOI 10.21203/rs.3.rs-2167175/v1
[18F]VUIIS1009B Features a Superior Imaging Performance to [18F]DPA-714 in TSPO Density Characterization for Neuroinflammatory PET ImagingSemantic proximity
Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers.Semantic proximity
Translocator Protein (18 kDa) Polymorphism (rs6971) Explains <i>in-vivo</i> Brain Binding Affinity of the PET Radioligand [ <sup>18</sup> F]-FEPPASemantic proximity
Quantification of the Specific Translocator Protein Signal of 18F-PBR111 in Healthy Humans: A Genetic Polymorphism Effect on In Vivo BindingSemantic proximity
Development and evaluation of [11C]DPA-813 and [18F]DPA-814: novel TSPO PET tracers insensitive to human single nucleotide polymorphism rs6971.Semantic proximity
Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation ImagingSemantic proximity
Feasibility study of TSPO quantification with [18F]FEPPA using population-based input function.Semantic proximity
First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony stimulating factor 1 receptorSemantic proximity
11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.Semantic proximity
Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission TomographySemantic proximity
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET ImagingSemantic proximity
Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.Semantic proximity
Select a neighboring publication to make it the new centre.