Article

Trained Immunity Causes Myeloid Cell Hypercoagulability

2024-07-18

Abstract excerpt

<h4>ABSTRACT</h4> Venous thromboembolism is common in individuals with chronic inflammatory diseases, but the pathogenic basis for this increased thrombotic risk remains poorly understood. Myeloid cell ‘trained immunity’ describes persistent innate immune cell memory arising from prior exposure to an inflammatory stimulus, leading to an enhanced immune response to subsequent unrelated stimuli. We identify enhance...

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Literature Corpus work: f9319af7-0095-5f82-8fbf-a3ac51d2b26e
DOI: 10.1101/2024.07.16.603679

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