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Article

Epigenetics and Trained Immunity.

Antioxidants & redox signaling - 10 Oct 2018

van der Heijden Charlotte D C C, Noz Marlies P, Joosten Leo A B, Netea Mihai G, Riksen Niels P, Keating Samuel T

Abstract excerpt

SIGNIFICANCE: A growing body of clinical and experimental evidence has challenged the traditional understanding that only the adaptive immune system can mount immunological memory. Recent findings describe the adaptive characteristics of the innate immune system, underscored by its ability to remember antecedent foreign encounters and respond in a nonspecific sensitized manner to reinfection. This has been termed...

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Identifiers

PMID: 28978221
DOI: 10.1089/ars.2017.7310
PMCID: PMC6121175

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