Article
OxLDL-mediated immunologic memory in endothelial cells.
Journal of molecular and cellular cardiology - 1 Sept 2020
Sohrabi Yahya, Lagache Sina M M, Voges Vivienne C, Semo Dilvin, Sonntag Glenn, Hanemann Irene, Kahles Florian, Waltenberger Johannes, Findeisen Hannes M
Abstract excerpt
Trained innate immunity describes the metabolic reprogramming and long-term proinflammatory activation of innate immune cells in response to different pathogen or damage associated molecular patterns, such as oxidized low-density lipoprotein (oxLDL). Here, we have investigated whether the regulatory networks of trained innate immunity also control endothelial cell activation following oxLDL treatment. Human...
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