Article

Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsy

2022-11-08

Abstract excerpt

<title>Abstract</title> <p>Background Drug resistance is a particular problem in patients with temporal lobe epilepsy, where seizures originate mainly from the hippocampus. Many of these epilepsies are acquired conditions following an insult to the brain such as a prolonged seizure and are characterized by pathophysiological mechanisms that synergistically mediate the secondary brain damage, prominently includin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f901e7ea-15cf-5a3f-bef8-5f2ff5987e4b
DOI: 10.21203/rs.3.rs-2189897/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nrf2 is predominantly expressed in hippocampal neurons in a rat model of temporal lobe epilepsyDOI 10.21203/rs.3.rs-2189897/v1Read

Normal and Pathological NRF2 Signalling in the Central Nervous SystemSemantic proximity Read

Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?Semantic proximity Read

Repurposing dimethyl fumarate as an antiepileptogenic and disease-modifying treatment for drug-resistant epilepsySemantic proximity Read

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy.Semantic proximity Read

Exploring oxidative stress pathways in epilepsySemantic proximity Read

Genistein Protects Epilepsy-Induced Brain Injury Through Regulating The JAK2/STAT3 and Keap1/Nrf2 Signaling Pathways in The Developing RatsSemantic proximity Read

The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic InterventionSemantic proximity Read

A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells.Semantic proximity Read

Association of KEAP1 and NFE2L2 polymorphisms with temporal lobe epilepsy and drug resistant epilepsy.Semantic proximity Read

Regulatory Dynamics of Nrf2 With Sirtuins in the Brain: Exploring Cellular Metabolism, Synaptic Plasticity, and Defense MechanismsSemantic proximity Read

Mechanistic insights into sevoflurane-induced hippocampal neuronal damage and cognitive dysfunction through the NEAT1/Nrf2 signaling axis in aged ratsSemantic proximity Read

The role of Nrf2 signaling pathways in nerve damage repairSemantic proximity Read