Article
A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells.
Cell transplantation - 1 Apr 2018
Ray S, Corenblum M J, Anandhan A, Reed A, Ortiz F O, Zhang D D, Barnes C A, Madhavan L
Abstract excerpt
Redox mechanisms are emerging as essential to stem cell function given their capacity to influence a number of important signaling pathways governing stem cell survival and regenerative activity. In this context, our recent work identified the reduced expression of nuclear factor (erythroid-derived 2)-like 2, or Nrf2, in mediating the decline in subventricular zone neural stem progenitor cell (NSPC) regeneration...
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